Figure 4From: Unravelling a fulvene based Replicator: Experiment and Theory in InterplayEnergy profile for templated reaction pathways. Inward pointing bridges cause repulsive interactions leading to a destabilizing interactions. The same effect also causes a higher energy for a preorganized A·B·NX* complex. The relative order of free energy profiles was calculated from average energies of MD simulations of the termolecular complexes.Back to article page