Table 2 Rate constants as defined in Figure 1 for thioester exchange and hydrolysis at the lipid bilayer interface in a DCL made from 13 and 14 at pH 8.0 and 40°C.
From: Dynamic combinatorial chemistry at the phospholipid bilayer interface
starting material | k 2 [M-1s-1] | k -2 [M-1s-1] | k 3 [M-1s-1] | k -3 [M-1s-1] | k h2 [s-1] | k h3 [s-1] |
|---|---|---|---|---|---|---|
13 | 1.65 × 10-2 ± 0.2 × 10-3 | 3.31 × 10-2 ± 0.8 × 10-3 | 1.32 × 10-2 ± 0.5 × 10-3 | 5.07 × 10-2 ± 2.7 × 10-3 | 0.008 × 10-2 ± 0.9 × 10-5 | 0.004 × 10-2 ± 0.6 × 10-4 |