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Figure 1 | Journal of Systems Chemistry

Figure 1

From: Evolution of metabolic networks: a computational frame-work

Figure 1

Overview of the simulation system. (A) Transcription of genes into catalytic ribozymes; (B) Assignment of catalytic functions to each ribozyme; (C) Estimation of reaction rates; (D) Construction and stochastic simulation of the metabolic network; (E) Metabolic Flux analysis and fitness evaluation; (F) Application of genetic variation operators.

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