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Journal of Systems Chemistry
Figure 1 | Journal of Systems Chemistry

Figure 1

From: Spontaneous absolute asymmetric synthesis promoted by achiral amines in conjunction with asymmetric autocatalysis

Figure 1

Asymmetric synthesis of pyrimidyl alkanol in the presence of achiral amines without the addition of a chiral substance; After the reaction between pyrimidine-5-carbaldehyde 1 and i -Pr 2 Zn in the presence of achiral amines, asymmetric autocatalysis amplified the spontaneously generated small fluctuation of ee to afford the enantiomerically enriched ( S )- or ( R )-5-pyrimidyl alkanol 2.

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