Scheme 1From: Enzymatic synthesis of DNA employing pyrophosphate-linked dinucleotide substratesSynthesis of compound I-VII. Reagents and conditions. (a) Ph3P, imidazole, dipyridyl disulfide, DMSO, rt.; (b) dNMP (N = A, T, G, C), 0.25 M N-ethylmorpholine buffer (pH = 8~8.5), Pd(NO3)2/ZnCl2, rt.Back to article page