Figure 2

Histogram of the absolute configuration and enantiomeric excess of pyrimidyl alkanol 2. The reaction of aldehyde 1 with i-Pr₂Zn in the presence of (a) N,N'-dimethylpiperazine 3, (b) N,N'-diethylpiperazine 4, (c). N-methylmorpholine 5, (d) total of (a), (b) and (c); stochastic behavior in the formation of (S)- and (R)-5-pyrimidyl alkanols 2 was observed in the presence of achiral amines 3-5, respectively.